Three researchers at the Marcus Institute for Aging Research in Boston, MA examine images of a brain scan.

What We Do

The Marcus Institute is helping older adults live more vital, meaningful lives through research that is changing standards of care. 

The Only Harvard Medical School Affiliate Solely Focused on Aging Research

Since 1966, the Hinda and Arthur Marcus Institute for Aging Research has challenged conventional wisdom to better understand how we age. The questions we ask - and the answers we uncover - directly impact standards of care and help seniors live more vital, meaningful lives.

The Marcus Institute is one of the largest gerontological research facilities in a clinical setting in the U.S. Our decades-long relationship with Harvard Medical School attracts expert teaching staff and outstanding research fellows. Our research portfolio increased 90% from 2010 to 2022 and ranks us in the top 10% of institutions funded by the National Institutes of Health.

Part of the Hebrew SeniorLife Network

Because the Marcus Institute operates within the Hebrew SeniorLife system, our researchers work in close proximity to more than 3,000 seniors each day, many of whom volunteer to participate in our studies, along with others from outside our system. Their needs, struggles, and challenges drive our work. Our results are used to develop services, programs, and best practices in the treatment of common conditions associated with aging.

Top Scientists in the Field of Aging

The Marcus Institute attracts the best and brightest minds in geriatric research. They are pioneers in fields including:

  • Non-invasive brain stimulation
  • Frailty
  • Delirium
  • Alzheimer’s disease
  • Dementia
  • Falls
  • Cardiology
  • Health care services
  • And more

Because we are a Harvard Medical School affiliate, our faculty is as invested in mentoring future researchers as they are in their own investigations. Our investigators are teachers, clinicians, and collaborators, with six faculty members holding full professor of medicine appointments at Harvard Medical School. Those they’ve trained have gone on to become leaders in their own right, including some within the Marcus Institute itself.

A Unique Interdisciplinary Approach

Aging is a complex biological process that affects all body systems. One of the Marcus Institute’s greatest and most unique strengths is our interdisciplinary nature. Experts in the brain work alongside experts in nutrition, cardiovascular function, genetics, pharmacology, health disparities, data analysis, and clinical trial development, to name just a few.

Our researchers work across fields to study areas such as frailty and its impact and measurement; ways to increase the quality of nursing home care; and non-invasive brain stimulation to improve Parkinson’s disease, depression, balance, memory, and more.

A researcher at the Marcus Institute for Aging Research in Boston, MA stands in front of a screen displaying a presentation. Other researchers are sitting around a table as he speaks and gestures toward them.
Experts in Aging Research

Meet Marcus Institute Researchers

The Marcus Institute is home to top investigators, teachers, clinicians, and collaborators who are passionate about improving the health of older adults.

Get to Know Our Experts
Dr. Shivani Sahni of the Marcus Institute for Aging Research in Boston, MA stands at the head of a conference table, presenting to five colleagues who are seated around the table. Behind Dr. Sahni is a screen where a slide with the title Protein & Osteoporosis is being projected.
Join a Talented Team

Work at the Marcus Institute

The Marcus Institute has opportunities for those who seek to build a career in research, whether you’re just starting or are an established investigator.

See Why We’re a Top Place to Work
Two staff members at the Marcus Institute for Aging Research in Boston work together on laptops.
Philanthropy fuels innovation

Donate to Aging Research

Marcus Institute donors provide critical funds to support early-stage research and junior investigators. Your investment will make it possible for every generation of seniors to be healthier than the last.

See How You Make a Difference

Research Areas

Learn more about the Marcus Institute’s areas of impact.

A researcher at the Marcus Institute for Aging Research in Boston, MA studies MRI images of a human brain.

Brain Health

Through pioneering multidisciplinary research, the Marcus Institute is uncovering new answers to the challenges of Alzheimer’s disease, dementia, delirium, and other changes to the brain.

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A researcher at the Marcus Institute for Aging Research in Boston, MA holds a vial of blood.

Biomarkers and Genetics

As precision medicine enters the mainstream of clinical care, Marcus Institute researchers are working to advance the understanding of disease biomarkers and genetics.

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A string of computer code is reflected in the glasses of a researcher at the Marcus Institute for Aging in Boston, MA.

Data Science and Technology

The Marcus Institute includes a biostatistics and data sciences faculty who collaborate with investigators to design and conduct clinical trials and observational studies in aging.

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A scene of a hospital floor at Hebrew Rehabilitation Center in Boston, MA, with a nurse standing and working on a computer in the background and a blood pressure monitor in the foreground.

Health Care Services and Policy

The Marcus Institute seeks to effect change in policies that impact the care of older adults by identifying age-related conditions that have an outsized impact on health care utilization and costs, while developing interventions that mitigate the issues.

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A close-up shot at two hands holding a syringe that is inserted in a vial of medication.


Marcus Institute researchers are examining the relationship between medicine and adverse health outcomes such as falls, injuries, and treatment side effects among older people.

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A research subject at the Marcus Institute for Aging Research stands on a measuring platform with a computer read-out reflected on the wall behind.

Physical Health and Function

Through the Marcus Institute’s research we are learning how older adults can maintain independence and quality of life.

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Addressing a Critical Need

The need has never been greater for the Marcus Institute’s focus on healthy longevity and expertise in improving quality of life as we age, both to reduce individual suffering and to lessen the burden on our health care system.


people turn 65 in the U.S. each day


of the U.S. population will be older adults by 2050

$700 billion

the Medicare federal budget in 2020