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Keep up-to-date with the latest news from the Hinda and Arthur Marcus Institute for Aging Research at Hebrew SeniorLife.

New Study Seeks to Guide Clinical Treatment for Older Patients with Aortic Stenosis

Boston – Why do some patients recover quickly after surgery, while others don’t? That is an important question when treating older frail patients suffering from aortic stenosis. Lead author Dae Hyun Kim, M.D., M.P.H., Sc.D., and principle investigator Director Lewis A. Lipsitz in the Marcus Institute for Aging Research at Hebrew SeniorLife explore this question in a paper published today in the Journal of the American Medical Association Internal Medicine.

Can testosterone plus exercise improve healing after hip fracture?

Women recovering from hip fractures sought for multicenter study

Boston — Researchers at the Hinda and Arthur Marcus Institute for Aging Research at Hebrew SeniorLife and Harvard Medical School are participating in a multicenter study exploring whether testosterone plus exercise can restore physical abilities in elderly women who have broken a hip.

A new “atlas” of genetic influences on osteoporosis will unlock better treatment options

Identifying more than 500 genetic determinants of bone mineral density, researchers expect to provide new opportunities for the development of novel drugs to prevent or treat osteoporosis

Study Reveals Best Tools for Measuring Severity of Delirium in Hospitalized Patients

Boston - A study published today in JAMA Internal Medicine reveals the best assessment tools available to establish the severity of diagnosed delirium in hospitalized patients. Delirium is a common, serious, and often preventable complication among older adult patients.

Promising New Imaging Method Aids Fracture Prediction

Deterioration in bone microstructure is an independent risk factor for fracture in older women and men

Research Study Sheds New Light on Relationship Between Genes and Bone Fracture Risk

Boston—A paper titled “Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomization study” appeared today in the British Medical Journal. The paper reports findings from a large international collaboration that identified 15 variations in the genome that are related to the risk of suffering bone fractures, which are a major healthcare problem affecting more than 9 million persons worldwide every year.

Hebrew SeniorLife’s Hinda and Arthur Marcus Institute for Aging Research establishes new center for clinical trials and interventional studies.

BOSTON — Hebrew SeniorLife’s Hinda and Arthur Marcus Institute for Aging Research has announced the establishment of the Interventional Studies in Aging Center (ISAC), the mission of which will be to develop and support clinical trials and intervention studies preserving and improving the health and quality of life of older individuals.

Proxies who watch advanced care planning video are more likely to withhold feeding tubes in end stage dementia

BOSTON — Researchers from Hebrew SeniorLife’s Hinda and Arthur Marcus Institute for Aging Research and Massachusetts General Hospital (MGH) have discovered that nursing home residents with advanced dementia are more likely to have advance directives that indicate they did should not get feeding tubes after their proxies viewed a 12-minute video on advance care planning. In addition, when proxies stated comfort was the goal of care, residents were more likely to have advance directives aligned with that goal.

Weight changes associated with reduced bone strength.

BOSTON — Researchers from Hebrew SeniorLife’s Hinda and Arthur Marcus Institute for Aging Research, Boston University, Beth Israel Deaconess Medical Center, and University of Calgary have found evidence that weight loss can result in worsening bone density, bone architecture and bone strength. The results were published in the Journal of Bone and Mineral Research.

Study shows proxies are less likely to use burdensome interventions when they believe patients with advanced dementia are nearing end of life.

BOSTON — Researchers from Hebrew SeniorLife’s Hinda and Arthur Marcus Institute for Aging Research have discovered that to begin with, proxies are a fairly accurate judge of the length of life left for their loved one with advanced dementia. Secondly, when proxies have judged that their loved one has less than 6 months to live they are more likely to have discussed goals of care with the health care team, and less likely to agree to burdensome interventions.

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