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Nutritional Epidemiology Current Research Projects

Mediterranean diet, related antioxidants and frailty
Boston Claude D. Pepper Center Older American Independence Centers (OAIC; 1P30AG031679)

The goal of this project is to determine the role of the Mediterranean diet (a diet rich in fruits, vegetables and dietary antioxidants) on the risk of frailty, and whether specific dietary antioxidants (vitamin C, E and carotenoids) represent an important part of the potential biologic pathway involving the Mediterranean diet and frailty.

Dairy food intake, related nutrients and frailty
National Dairy Council

The goal of this project is to determine the role of dairy foods intake on the risk of frailty over time, and whether dairy specific nutrients such as dietary protein, calcium, and vitamin D represent an important part of the biologic pathway involving dairy food intake and frailty.

The effect of sodium reduction on blood pressure and physical function in older adults: Satter hOuse Trial of Reduced sodiUm mEals (SOTRUE)
 Interventional Studies in Aging Center, Marcus Institute, Hebrew SeniorLife; NCT04074941

The goal of this pilot study is to determine the effects of a low sodium (<2.3 g/d), 2-week meal plan compared with a usual meal plan (average sodium >4.5 g/d) on seated blood pressure among independently living older adults using an individual level, parallel RCT.

Dietary inflammatory index, depression, and frailty
NIA T32-AG023480

The goal of this project is to establish the association between the dietary inflammatory index (DII, marker of dietary inflammatory) and frailty, and to determine if depression modified this association.

Risk Factors for Age Related Bone Loss

This is the fourth, five-year continuation of this project examining both genetic and lifestyle factors influencing age-related bone loss and fractures. The project involves the performance of a genome-wide association study of genes responsible for bone density and quantitative ultrasound. It also examines diet by gene interactions and the role of lean leg mass on the risk of hip fracture.