Here is a list of Clinical Trials which are being supported by the Interventional Studies in Aging Center (ISAC), as of March, 2019.
| Project /Study Name | HSL PI | Design | ClinicalTrials.gov Listing |
|---|---|---|---|
| The feasibility of combining noninvasive brain stimulation and physical therapy to improve gait and balance in older adults with recent falls | O.Y. Lo, PhD | Double-blind randomized pilot clinical trial | N/A |
| The effect of sodium reduction on blood pressure and physical function in older adults | S. Sahni, PhD | Randomized pilot clinical trial | N/A |
| Omega-3 PUFAs for the Vascular Component of Age-Related Cognitive Decline (PUFA Trial) | G. Bowman | Randomized, Double-Blind Placebo-Controlled Trial | NCT01953705 |
| Trial to Reduce Antimicrobial use in Nursing Home Residents with Alzheimer’s and Other Dementias (TRAIN-AD) | S. Mitchell | Cluster Randomized Blinded Trial | NCT03244917 |
| Pragmatic Trial of Video Education in Nursing Homes (PROVEN) | S. Mitchell | Cluster Randomized Blinded Trial | NCT02612688 |
| Health Outcomes of Tai-Chi in Subsidized Senior Housing (MiWish) | L. Lipsitz | Cluster Randomized Blinded Trial | NCT02346136 |
| Combining Testosterone Therapy and Exercise to Improve Function Post Hip Fracture (STEP-HI) | D. Kiel* | Randomized, Placebo-Controlled Trial | NCT02938923 |
| Effects of Multi-focal Transcranial Direct Current Stimulation (tDCS) on Motor-Cognitive Dysfunctions in Parkinson's Disease | B. Manor | Blinded, Randomized Trial | NCT02656316 |
| The Short-term Effects of Noninvasive Electrical Brain Stimulation on Dual Tasking in Older Adults | B. Manor | Blinded, Randomized Crossover Trial | NCT03191812 |
| Effect of Transcranial Direct Current Stimulation (tDCS) on Motor and Cognitive Functions in Idiopathic Fallers | B. Manor | Blinded, Randomized Trial | NCT02954328 |
*HSL is one of the clinical sites for this multi-center trial, which has multiple PI’s: Ellen Binder, MD; Jay Magaziner, PhD; and Kenneth Schectman, PhD. The data coordinating center is at Washington University, St Louis.
There are many additional interventional research studies which our Biostatistics Core support, listed here: https://www.marcusinstituteforagingresearch.org/research/biostatistics/current-projects.
In addition, each center at the Hinda and Arthur Marcus Institute for Aging Research maintains a list of current projects on this website. These studies are primarily non-interventional, long-term cohort studies.
