Here is a list of Clinical Trials which are being supported by the Interventional Studies in Aging Center (ISAC), as of March, 2019.
|Project /Study Name||HSL PI||Design||ClinicalTrials.gov Listing|
|The feasibility of combining noninvasive brain stimulation and physical therapy to improve gait and balance in older adults with recent falls||O.Y. Lo, PhD||Double-blind randomized pilot clinical trial||N/A|
|The effect of sodium reduction on blood pressure and physical function in older adults||S. Sahni, PhD||Randomized pilot clinical trial||N/A|
|Omega-3 PUFAs for the Vascular Component of Age-Related Cognitive Decline (PUFA Trial)||G. Bowman||Randomized, Double-Blind Placebo-Controlled Trial||NCT01953705|
|Trial to Reduce Antimicrobial use in Nursing Home Residents with Alzheimer’s and Other Dementias (TRAIN-AD)||S. Mitchell||Cluster Randomized Blinded Trial||NCT03244917|
|Pragmatic Trial of Video Education in Nursing Homes (PROVEN)||S. Mitchell||Cluster Randomized Blinded Trial||NCT02612688|
|Health Outcomes of Tai-Chi in Subsidized Senior Housing (MiWish)||L. Lipsitz||Cluster Randomized Blinded Trial||NCT02346136|
|Combining Testosterone Therapy and Exercise to Improve Function Post Hip Fracture (STEP-HI)||D. Kiel*||Randomized, Placebo-Controlled Trial||NCT02938923|
|Effects of Multi-focal Transcranial Direct Current Stimulation (tDCS) on Motor-Cognitive Dysfunctions in Parkinson's Disease||B. Manor||Blinded, Randomized Trial||NCT02656316|
|The Short-term Effects of Noninvasive Electrical Brain Stimulation on Dual Tasking in Older Adults||B. Manor||Blinded, Randomized Crossover Trial||NCT03191812|
|Effect of Transcranial Direct Current Stimulation (tDCS) on Motor and Cognitive Functions in Idiopathic Fallers||B. Manor||Blinded, Randomized Trial||NCT02954328|
*HSL is one of the clinical sites for this multi-center trial, which has multiple PI’s: Ellen Binder, MD; Jay Magaziner, PhD; and Kenneth Schectman, PhD. The data coordinating center is at Washington University, St Louis.
There are many additional interventional research studies which our Biostatistics Core support, listed here: https://www.marcusinstituteforagingresearch.org/research/biostatistics/current-projects.
In addition, each center at the Hinda and Arthur Marcus Institute for Aging Research maintains a list of current projects on this website. These studies are primarily non-interventional, long-term cohort studies.