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Current Projects

Here is a list of Clinical Trials which are being supported by the Interventional Studies in Aging Center (ISAC), as of November, 2019.


Project /Study NameHSL Listing
Imbedded Pragmatic AD/ADRD Clinical Trials Collaboratory (NIA IMPACT)S. MitchellInfrastructure GrantN/A
Nursing Home Prevention of Injury in Dementia (NH-PRIDE)S. BerryNon-randomized implementation trialN/A
The feasibility of combining noninvasive brain stimulation and physical therapy to improve gait and balance in older adults with recent fallsO.Y. LoRandomized pilot clinical trialN/A
The effect of sodium reduction on blood pressure and physical function in older adultsS. SahniRandomized pilot clinical trialN/A
Efficacy of Nutritional Supplementation on Physical-activity Mediated Charges in Physical Functioning Older Adults at Risk for Mobility Disability (The VIVE2 Study)T. TravisonRandomized Controlled TrialNCT01542892
Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE)T. TravisonPragmatic Cluster Randomized Controlled TrialNCT02475850
Effects of Tai Chi on Frailty in Elderly AdultsL. LipsitzMatched Cluster Randomized Controlled TrialNCT01126723
Optimizing Protein Inake in Older Americans With Mobility Limitations (OPTIMen)T. TravisonTwo-by-two Factorial Randomized Controlled TrialNCT01275365
Trial to Reduce Antimicrobial use in Nursing Home Residents with Alzheimer’s and Other Dementias (TRAIN-AD)S. MitchellCluster Randomized TrialNCT03244917
Pragmatic Trial of Video Education in Nursing Homes (PROVEN)S. MitchellCluster Randomized TrialNCT02612688
Combining Testosterone Therapy and Exercise to Improve Function Post Hip Fracture (STEP-HI)D. Kiel*Randomized, Placebo-Controlled TrialNCT02938923
Effects of Multi-focal Transcranial Direct Current Stimulation (tDCS) on Motor-Cognitive Dysfunctions in Parkinson's DiseaseB. ManorRandomized TrialNCT02656316
The Short-term Effects of Noninvasive Electrical Brain Stimulation on Dual Tasking in Older AdultsB. ManorRandomized Crossover TrialNCT03191812

*HSL is one of the clinical sites for this multi-center trial, which has multiple PI’s:  Ellen Binder, MD; Jay Magaziner, PhD; and Kenneth Schectman, PhD. The data coordinating center is at Washington University, St Louis.