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Current Projects

Here is a list of Clinical Trials which are being supported by the Interventional Studies in Aging Center (ISAC), as of March, 2019.


Project /Study NameHSL Listing
The feasibility of combining noninvasive brain stimulation and physical therapy to improve gait and balance in older adults with recent fallsO.Y. Lo, PhDDouble-blind randomized pilot clinical trialN/A
The effect of sodium reduction on blood pressure and physical function in older adultsS. Sahni, PhDRandomized pilot clinical trialN/A
Omega-3 PUFAs for the Vascular Component of Age-Related Cognitive Decline (PUFA Trial)G. BowmanRandomized, Double-Blind Placebo-Controlled TrialNCT01953705
Trial to Reduce Antimicrobial use in Nursing Home Residents with Alzheimer’s and Other Dementias (TRAIN-AD)S. MitchellCluster Randomized Blinded TrialNCT03244917
Pragmatic Trial of Video Education in Nursing Homes (PROVEN)S. MitchellCluster Randomized Blinded TrialNCT02612688
Health Outcomes of Tai-Chi in Subsidized Senior Housing (MiWish)L. LipsitzCluster Randomized Blinded TrialNCT02346136
Combining Testosterone Therapy and Exercise to Improve Function Post Hip Fracture (STEP-HI)D. Kiel*Randomized, Placebo-Controlled TrialNCT02938923
Effects of Multi-focal Transcranial Direct Current Stimulation (tDCS) on Motor-Cognitive Dysfunctions in Parkinson's DiseaseB. ManorBlinded, Randomized TrialNCT02656316
The Short-term Effects of Noninvasive Electrical Brain Stimulation on Dual Tasking in Older AdultsB. ManorBlinded, Randomized Crossover TrialNCT03191812
Effect of Transcranial Direct Current Stimulation (tDCS) on Motor and Cognitive Functions in Idiopathic FallersB. ManorBlinded, Randomized TrialNCT02954328

*HSL is one of the clinical sites for this multi-center trial, which has multiple PI’s:  Ellen Binder, MD; Jay Magaziner, PhD; and Kenneth Schectman, PhD. The data coordinating center is at Washington University, St Louis.

There are many additional interventional research studies which our Biostatistics Core support, listed here:

In addition, each center at the Hinda and Arthur Marcus Institute for Aging Research maintains a list of current projects on this website. These studies are primarily non-interventional, long-term cohort studies.