STAMINA Study

Senolytics to Alleviate Mobility Issues and Neurological Impairment in Aging

  1. Join a Research Study
  2. STAMINA Study

Join a Clinical Trial Exploring New Treatments to Increase Mobility and Improve Memory

Are you age 65 or older and concerned about your mobility and memory?

The STAMINA Study at the Hinda and Arthur Marcus Institute for Aging Research in Boston is seeking participants. STAMINA stands for Senolytics to Alleviate Mobility Issues and Neurological Impairment in Aging.

STAMINA Study Goals

The goal of the study is to determine whether the senolytic medications Dasatinib and Quercetin can reduce senescent cells, increase mobility (walking speed), and improve memory in older adults.

STAMINA Study Participation Overview

The STAMINA Study involves:

  • Up to 8 visits, one every two weeks, over 14 weeks
  • Eligibility screening visit
  • Health interviews, walking, balance, memory, and blood flow assessments at baseline, and follow up visits
  • Blood tests at each visit
  • Two urine tests
  • Dasatinib and Quercetin will be given at six study visits (visits two through seven) with one dose to take at home the next day following the visit for a total of 12 doses
  • Regular telephone follow up with the study team throughout the study
  • Compensation of up to $300
  • Free parking and/or transportation provided

Visits take place at the Marcus Institute’s Roslindale location. Free parking and/or transportation can be provided.

How to Sign Up

If you’re interested in participating in the STAMINA Study, send us an email or call 617-971-5688.

Download a flyer
 

Study Faculty

View Marcus Institute researchers leading the STAMINA study.
Professional Headshot Photo of Marcus Institute for Aging Research Director, Lewis Lipsitz, MD

Lewis Lipsitz, MD

  • Director, Hinda and Arthur Marcus Institute for Aging Research
  • Chief Academic Officer, Irving and Edyth S. Usen and Family Chair in Medical Research, Hebrew SeniorLife
  • Professor of Medicine, Harvard Medical School
  • Chief, Division of Gerontology, Beth Israel Deaconess Medical Center
Photo of Courtney Millar, PhD at the Hinda and Arthur Marcus Institute for Aging Research in Boston, MA

Courtney Millar, PhD

  • Assistant Scientist
  • Instructor in Medicine, Harvard Medical School and Beth Israel Deaconess Medical Center

Research Areas

A researcher at the Marcus Institute for Aging Research in Boston, MA studies MRI images of a human brain.

Brain Health

Through pioneering multidisciplinary research, the Marcus Institute is uncovering new answers to the challenges of Alzheimer’s disease, dementia, delirium, and other changes to the brain.

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A close-up shot at two hands holding a syringe that is inserted in a vial of medication.

Medication

Marcus Institute researchers are examining the relationship between medicine and adverse health outcomes such as falls, injuries, and treatment side effects among older people.

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A research subject at the Marcus Institute for Aging Research stands on a measuring platform with a computer read-out reflected on the wall behind.

Physical Health and Function

Through the Marcus Institute’s research we are learning how older adults can maintain independence and quality of life.

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