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Current Projects

Here is a list of Clinical Trials which are being supported by the Interventional Studies in Aging Center (ISAC), as of June, 2019.


Project /Study NameHSL Listing
Imbedded Pragmatic AD/ADRD Clinical Trials Collaboratory (NIA IMPACT)S. MitchellInfrastructure GrantN/A
Nursing Home Prevention of Injury in Dementia (NH-PRIDE)S. BerryNon-randomized implementation trialN/A
The feasibility of combining noninvasive brain stimulation and physical therapy to improve gait and balance in older adults with recent fallsO.Y. LoRandomized pilot clinical trialN/A
The effect of sodium reduction on blood pressure and physical function in older adultsS. SahniRandomized pilot clinical trialN/A
Trial to Reduce Antimicrobial use in Nursing Home Residents with Alzheimer’s and Other Dementias (TRAIN-AD)S. MitchellCluster Randomized TrialNCT03244917
Pragmatic Trial of Video Education in Nursing Homes (PROVEN)S. MitchellCluster Randomized TrialNCT02612688
Combining Testosterone Therapy and Exercise to Improve Function Post Hip Fracture (STEP-HI)D. Kiel*Randomized, Placebo-Controlled TrialNCT02938923
Effects of Multi-focal Transcranial Direct Current Stimulation (tDCS) on Motor-Cognitive Dysfunctions in Parkinson's DiseaseB. ManorRandomized TrialNCT02656316
The Short-term Effects of Noninvasive Electrical Brain Stimulation on Dual Tasking in Older AdultsB. ManorRandomized Crossover TrialNCT03191812

*HSL is one of the clinical sites for this multi-center trial, which has multiple PI’s:  Ellen Binder, MD; Jay Magaziner, PhD; and Kenneth Schectman, PhD. The data coordinating center is at Washington University, St Louis.